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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM173
All Species:
18.48
Human Site:
Y240
Identified Species:
58.1
UniProt:
Q86WV6
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WV6
NP_938023.1
379
42193
Y240
A
G
I
K
D
R
V
Y
S
N
S
I
Y
E
L
Chimpanzee
Pan troglodytes
XP_517967
379
42237
Y240
A
G
I
K
D
R
V
Y
S
N
S
I
Y
E
L
Rhesus Macaque
Macaca mulatta
XP_001084311
379
42174
Y240
A
G
I
K
D
R
V
Y
S
N
S
I
Y
E
L
Dog
Lupus familis
XP_848338
422
46753
Y284
A
G
I
K
R
R
V
Y
T
N
S
V
Y
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TBT3
378
42811
Y239
A
G
I
K
N
R
V
Y
S
N
S
V
Y
E
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518396
175
19310
L38
H
C
D
V
R
D
D
L
Q
G
A
D
P
A
V
Chicken
Gallus gallus
XP_001232171
395
44204
E247
Q
Y
L
A
D
L
P
E
T
I
L
T
R
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699489
398
45281
S231
R
A
G
V
R
K
R
S
Y
T
N
S
V
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
93.1
68.9
N.A.
68.8
N.A.
N.A.
20.3
41.7
N.A.
35.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
93.6
76.5
N.A.
81
N.A.
N.A.
31.6
56.7
N.A.
49.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
N.A.
N.A.
0
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
13.3
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
63
13
0
13
0
0
0
0
0
0
13
0
0
25
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
50
13
13
0
0
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
13
0
0
0
0
0
63
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
63
13
0
0
0
0
0
0
13
0
0
0
0
13
% G
% His:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
63
0
0
0
0
0
0
13
0
38
0
0
13
% I
% Lys:
0
0
0
63
0
13
0
0
0
0
0
0
0
0
13
% K
% Leu:
0
0
13
0
0
13
0
13
0
0
13
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
63
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
13
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
38
63
13
0
0
0
0
0
13
0
0
% R
% Ser:
0
0
0
0
0
0
0
13
50
0
63
13
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
25
13
0
13
0
0
0
% T
% Val:
0
0
0
25
0
0
63
0
0
0
0
25
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
0
63
13
0
0
0
63
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _